Nabusafe (Nabumetone) Tablets by Life Pharmaceutical Company

Nabusafe 500mg Tablet

Drug Catagory: Cyclooxygenase 2 Inhibitors, 2 Analgesics, antipyretics, NSAIDs, antigout, and antirheumatics


Each Tablet contains:

  • Nabumetone…………….500mg

Pharmacological Action:

  • Nabumetone: is a naphthylalkanone. Is is a non-selective prostaglandin G/H synthase (a.k.a. cyclooxygenase or COX) inhibitor that acts on both prostaglandin G/H synthase 1 and 2 (COX-1 and -2). Prostaglandin G/H synthase catalyzes the conversion of arachidonic acid to prostaglandin G2 and prostaglandin G2 to prostaglandin H2. Prostaglandin H2 is the precursor to a number of prostaglandins involved in fever, pain, swelling, inflammation, and platelet aggregation. The parent compound is a prodrug that undergoes hepatic biotransformation to the active compound, 6-methoxy-2-naphthylacetic acid (6MNA). The analgesic, antipyretic and anti-inflammatory effects of NSAIDs occur as a result of decreased prostaglandin synthesis.


  • Tablet

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