Vermolif Syrup (Piperazine Citrate) by Life Pharmaceutical Company

Drug Category: Antinematodal Agents/Anthelmintics

Indication: Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.

Composition:

Each 5ml contains:

• Piperazine Citrate eq.to Piperazine Hydrate………….500mg

Pharmacological Action:

• Piperazine: Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children.Piperazine is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.

Presentation:

• Amber Glass Bottle
• Syrup in High Density Polyethylene Bottle

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