Coreg Tablets (Carvedilol) by Life Pharmaceutical Company

Drug Category: Alpha/Beta Blocker

Indication: Carvedilol is primarily indicated in conditions like Adjunct in heart failure, Angina, Angina pectoris, Cardiac arrhythmia, Cardiomyopathy, Congestive heart failure, Essential hypertension, Hypertension, Sedation for surgical and diagnostic proceduers, Sedation in intensive care, and can also be given in adjunctive therapy as an alternative drug of choice in Maintenance of anaesthesia, Myocardial infarction.


Each Tablet contains:

  • Carvedilol………………………………25mg

Pharmacological Action:

  • Carvedilol: Carvedilol is a racemic mixture in which nonselective beta-adrenoreceptor blocking activity is present in the S(-) enantiomer and alpha-adrenergic blocking activity is present in both R(+) and S(-) enantiomers at equal potency. Carvedilol’s beta-adrenergic receptor blocking ability decreases the heart rate, myocardial contractility, and myocardial oxygen demand. Carvedilol also decreases systemic vascular resistance via its alpha adrenergic receptor blocking properties. Carvedilol and its metabolite BM-910228 (a less potent beta blocker, but more potent antioxidant) have been shown to restore the inotropic responsiveness to Ca2+ in OH- free radical-treated myocardium. Carvedilol and its metabolites also prevent OH- radical-induced decrease in sarcoplasmic reticulum Ca2+-ATPase activity. Therefore, carvedilol and its metabolites may be beneficial in chronic heart failure by preventing free radical damage.


  • Tablets

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