Mectin Tablets (Ivermectin) by Life Pharmaceutical Company
Drug Category: Anthelmintics
Indication: Ivermectin is primarily indicated in conditions like Lymphatic filariasis, Onchoceriasis, Strongyloides stercoralis, Strongyloidiasis.
Each Tablet contains:
- Ivermectin: Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding causes an increase in the permeability of the cell membrane to chloride ions and results in hyperpolarization of the cell, leading to paralysis and death of the parasite. Ivermectin also is believed to act as an agonist of the neurotransmitter gamma-aminobutyric acid (GABA), thereby disrupting GABA-mediated central nervous system (CNS) neurosynaptic transmission. Ivermectin may also impair normal intrauterine development of O. volvulus microfilariae and may inhibit their release from the uteri of gravid female worms.