Sotis Tablets (Atorvastatin as Calcium Salt) by Life Pharmaceutical Company
Drug Category: Lipid-regulating drugs /Anti-atheromas
Indication: Atorvastatin is primarily indicated in conditions like Familial hypercholesterolaemia, Homozygous familial hypercholesterolemia, Hypercholesterolaemia, Hyperlipoproteinaemia, Hypertriglyceridaemia, NSAID-associated gastric and duodenal ulcers and duodenal errosions.
Each Tablet contains:
- Atorvastatin as Calcium Salt…………………….20mg/ 40mg
- Atorvastatin: Atorvastatin selectively and competitively inhibits the hepatic enzyme HMG-CoA reductase. As HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate in the cholesterol biosynthesis pathway, this results in a subsequent decrease in hepatic cholesterol levels. Decreased hepatic cholesterol levels stimulates upregulation of hepatic LDL-C receptors which increases hepatic uptake of LDL-C and reduces serum LDL-C concentrations.