F-Con Capsules (Fluconazole) by Life Pharmaceutical Company

Drug Category: Antifungal Triazole

Indication:  Fluconazole is primarily indicated in conditions like Adjunct in heart failure, Adjunct in stable moderate to severe heart failure, Adjunctive therapy without valproate, All forms of epilepsy, Candidiasis, Fungal infection, Hormone-mediated secretory diarrhea, Hormone-mediated secretory diarrhea (but can be of benefit in refactory cases), Hormone-mediated secretory diarrhea (can be benefit in refactory cases), Nausea and vomiting, Neurogenic bladder, Oropharangeal candidiasis, Parkinsonism, Pityriasis versicolor, Tinea pedis, Vaginal infections, and can also be given in adjunctive therapy as an alternative drug of choice in Bone marrow transplantation.
Composition:

Each Capsule contains:

• Fluconazole………………………………………………………150mg/ 200mg/ 50mg

Pharmacological Action:

• Fluconazole: Fluconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Fluconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.

Presentation:

• Capsules

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