Xonelif Injections (Ceftriaxone) by Life Pharmaceutical Company

Drug Category: Cephalosporin

Indication: Severe respiratory and genitourinary tract, bone and joint, abdominal infection, sepsis, meningitis. For the treatment of the infections (respiratory , skin , soft tissue , UTI , ENT) caused by S. pneumonia, H. influenza , staphylococci, S. pyogenes (group A beta-hemolytic streptococci) , E.coli, P, mirabilis, Klebsiella, cogulase-negative staph.

Composition:

Each Vial Contains:   

• Ceftriaxone………..250mg, 500mg, 1gm

Pharmacological Action:

Ceftriaxone: Ceftriaxone is a cephalosporin/cephamycin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. Ceftriaxone has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of Ceftriaxone results from the inhibition of cell wall synthesis and is medicated through Ceftriaxone binding to penicillin binding proteins (PBPs). Ceftriaxone works by inhibiting the mucopeptide synthesis in the bacterial cell wall. The beta-lactam moiety of Ceftriaxone binds to carboxypeptidases, endopeptidases, and transpeptidases in the bacterial cytoplasmic membrane. These enzymes are involved in cell-wall synthesis and cell division. By binding to these enzymes, Ceftriaxone results in the formation of defective cell walls and cell death.

Presentation:

• Injection in ampoule

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