Azgard Suspension (Albendazole) by Life Pharmaceutical Company
Drug Category: Anthelmintics/ Antiprotozoal Agents/ Tubulin Modulators
Indication: For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
Composition:
Each 5ml contains:
- Albendazole…………………………….……..200mg
Pharmacological Action:
- Albendazole: Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies.
Presentation:
- Amber Glass Bottle
- Syrup in High Density Polyethylene Bottle
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