Hemolif Syrup (Vit. B. Complex + Iron) by Life Pharmaceutical Company
Drug Category: Haematinic/ vitamins
Indication: General disability, anorexia, undue fatigue, nervous exhaustion, decreased resistance to infection, delayed growth development in children, preparation for surgery, pernicious anemia, liver disorders and vitamin deficiency
Composition:
Each 100ml contain
- Ferric Amm.Citrate………900mg
- Folic Acid………………10mg
- Thiamine HCl…………….20mg
- Pyridoxine HCl…………..40mg
- Nicotinamide……………200mg
Pharmacological Action:
- Ferric Ammonium Citrate: Ferric Amm. Citrate improves the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. It is used in the treatment of anemia. Its main component is iron. Iron is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron stores may result in iron-deficiency anemia. Iron is used to build up the blood in anemia.
- Folic acid: Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase. These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids,interconvert amino acids, methylate tRNA, and generate and use formate. Using vitamin B12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase.
- Thiamin HCl: Thiamine is a vitamin with antioxidant, erythropoietic, cognition-and mood-modulatory, antiatherosclerotic, putative ergogenic, and detoxification activities. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Inhibition of endothelial cell proliferation may also promote atherosclerosis. The neuronal death is associated with increased free radical production, suggesting that oxidative stress may play an important early role in brain damage associated with thiamine deficiency. It is thought that the mechanism of action of thiamine on endothelial cells is related to a reduction in intracellular protein glycation by redirecting the glycolytic flux.
- Pyridoxine HCl: Vitamin B6 (pyridoxine) is a water-soluble vitamin used in the prophylaxis and treatment of vitamin B6 deficiency and peripheral neuropathy in those receiving isoniazid (isonicotinic acid hydrazide, INH). Vitamin B6 has been found to lower systolic and diastolic blood pressure in a small group of subjects with essential hypertension. Another study showed pyridoxine hydrochloride to inhibit ADP- or epinephrine-induced platelet aggregation and to lower total cholesterol levels and increase HDL-cholesterol levels. Vitamin B6, principally in the form of the coenzyme pyridoxal 5′-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, nor epinephrine and gamma-aminobutyric acid (GABA).
- Nicotinamide: An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of black tongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. Nicotinamide has demonstrated anti-inflammatory actions which may be of benefit in patients with inflammatory skin conditions. These conditions include acne vulgaris, and the compound can suppress antigen induced-lymphocytic transformation and inhibit of 3′-5′ cyclic AMP phosphodiesterase. Nicotinamide has demonstrated the ability to block the inflammatory actions of iodides known to precipitate or exacerbate inflammatory acne.
Presentation:
- Syrup in Amber Glass Bottle
- Syrup in High Density Polyethylene Bottle
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