Lukin Tablet (Montelukast) by Life Pharmaceutical Company
Drug Category: Anti-Asthmatic Agents
Indication: For the treatment of asthma.
Composition:
Each Tablet contains:
- Montelukast as Sodium …………..5mg
Pharmacological Action:
- Montelukast: Montelukast, like zafirlukast, is a leukotriene receptor antagonist used as an alternative to anti-inflammatory medications in the management and chronic treatment of asthma and exercise-induced bronchospasm (EIB). Unlike zafirlukast, montelukast does not inhibit CYP2C9 or CYP3A4 and is, therefore, not expected to affect the hepatic clearance of drugs metabolized by these enzymes. Montelukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Montelukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Presentation:
- Tablet
- Chewable Tablet
- Sachet