Voltan Tablets (Valsartan) by Life Pharmaceutical Company
Drug Category: Angiotensin II receptor anatgonists
Indication: Valsartan is primarily indicated in conditions like Chronic congestive heart failure, Hypertension, Myocardial infarction.
Each Tablet contains:
- Valsartan: Valsartan is an ARB that selectively inhibits the binding of angiotensin II to AT1, which is found in many tissues such as vascular smooth muscle and the adrenal glands. This effectively inhibits the AT1-mediated vasoconstrictive and aldosterone-secreting effects of angiotensin II and results in a decrease in vascular resistance and blood pressure. Valsartan is selective for AT1 and has virtually no affinity for AT2. Inhibition of aldosterone secretion may inhibit sodium and water reabsorption in the kidneys while decreasing potassium excretion. The primary metabolite of valsartan, valeryl 4-hydroxy valsartan, has no pharmacological activity.